Ctsu active protocols and accrual report

Covenant Clinic Active Protocols 01/01/2013
Breast Cancer
Activation
Protocol
Protocol ID
Accrued Patients
Protocol Title
Renewals
Amgen 20110147
the effect of prophylactic intervention with 12-056 CCTC
naproxen or loratadine on bone pain in breast cancer subjects receiving chemotherapy and pegfilgrastim SCUSF-0806
Phase II placebo-controlled trial of lisinopril and coreg CR to reduce cardiotoxicity in 11-030 CCTC
patients with breast cancer receiving (neo)adjuvant chemotherapy with trastuzumab (Herceptin) EGF 114299
A Phase III trial to compare the safety and efficacy of lapatinib plus trastuzumab plus 11-010-CCTC
an aromatase inhibitor (AI) versus trastuzumab plus an AI versus lapatinib plus an AI as first-line therapy in postmenopausal subjects with hormone receptor positive, HER2-positive metastatic breast cancer (MBC) who have received trastuzumab and endocrine therapy in the neo/adjuvant setting A Phase III, Randomized Clinical Trial of 11-012 CCTC
Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER-2 Negative Breast Cancer with Recurrence Score (RS) of 25 or Less NSABP B-49
A Phase III Clinical Trial Comparing the 12-030 CIRB
Combination of Docetaxel plus Cyclophosphamide to Anthracycline Based Chemotherapy Regimens for Women with Node-Positive or High Risk Node-Negative Her2-Neg. Breast Cancer NSABP B-47
A Randomized Phase III Trial of Adjuvant 11-013 CIRB
Node-Negative HER2-Low Invasive Breast Cancer. NSABP B-43
08-044-CCTG
Alone for Women with HER2-Positive Ductal Carcinoma in Situ Resected by Lumpectomy Agendia PROMIS
breast cancer patient with an Intermedicate Cancer Control
Activation
Protocol
Protocol ID
Protocol Title
Renewals
Genomics of Brain Tumors and CNS
(Dr Ryken)
CDX110-04
(Dr. Ryken)
Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma 12-019 CCTC
Lenalidomide vs Azacitidine Alone vs. Azacitidine in Combination with Vorinostat for Higher-Risk Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML) Connect CLL
Gastrointestinal Cancer
Activation
Protocol
Protocol ID
Protocol Title
Renewals
12-014 CCTC
Patients Based on ERCC 1 (Excision Repair Cross-Complementing 1) for Advanced/Metastatic Esophageal, gastric, or Gastroesophageal Junction (GEJ) Cancer NSABP P-5
Statin Polyp Prevention Trial in Patients CALGB 80702
A Phase III Trial of 6 versus 12 Treatments Placebo for Patients with Resected Stage Genitourinary Cancer
Activation
Protocol
Protocol ID
Accrued Patients
through Protocol Title
Renewals

Lung Cancer
Activation
Protocol
Protocol ID
Accrued Patients
Protocol Title
Renewals
Pemetrexed or Both Following Carboplatin, CIRB 10-037
A Phase III Randomized Trial Of Adjuvant 4cm) -IIIA Non-Small Cell Lung Cancer (NSCLC) Melanoma
Activation
Protocol
Protocol ID
Protocol Title
Renewals
A Phase III Randomized Study of Adjuvant Activation
Protocol
Protocol ID
Accrued Patients
Protocol Title
Renewals
09-058-CCTC
Connect MM

Source: http://www.wheatoniowa.org/webres/File/services/Cancer%20Treatment/Open%20Protocols%20January%202013.pdf