PUBLICATIONS OF SANDRA C. MILLER Research Papers in Peer-Reviewed Scientific Journals
(Papers directly related to the cancer-fighting diet are highlighted)
Miller, S.C., Delorme, D. and Shan, J. (2009) CVT-E002, a proprietary extract of Panax quinquefolius,
stimulated the immune system and significantly extends the life span of leukemic mice: Analysis of the hemopoietic and immune cells in vivo. Journal of the Society for Integrative Oncology (in press).
Miller, S.C., Delorme, D. (2008) An extract of North American ginseng, Panax quinquefolius, stimulates
spontaneous immunity in infant mice: Sustained, augmented immunity in adulthood long after withdrawal of the extract. Journal of Complementary and Integrative Medicine 5(1): 1-16.
Brousseau, M. and Miller, S.C. (2007) The effects of Echinacea root extract in plasmacytoma-bearing
mice: Enhancement of non-specific immunity. Journal of Herbs & Medicinal Plants 13(2):11-23 .
Miller, S.C., Pandi, P.S.R., Esquifino, A.I., Cardinali, D.P. and Maestroni, G.J.M. (2006) The role of
melatonin in immuno-enhancement: Potential application in cancer. Journal of Experimental Pathology 87(2): 81-87.
Chow, G., Johns, T., and Miller, S.C. (2006) Dietary Echinacea purpurea during murine pregnancy: Effect
on maternal hemopoiesis and fetal growth. Biology of the Neonate 89: 133-138.
Srinivasan, V., Maestroni, G.J.M., Cardinali, D.P., Esquifini, A.I., Pandi-Perumal, S.R., and Miller,
S.C.(2005) Melatonin, immune function and aging. Immunity & Ageing 2: 17-49.
Delorme, D. and Miller, S.C. (2005) Dietary consumption of the herb, Echinacea, by mice afflicted with
autoimmune (type I) diabetes: The effect on their hemopoietic and immune cells is feeding duration dependent. Autoimmunity 38(6): 453-461.
Miller, S.C. (2005) Echinacea: A miracle herb against aging and cancer? Evidence in vivo in mice. eCAM: Evidence-based Complementary and Alternative Medicine 2(3): 309-314.
Brousseau, M. and Miller, S.C. (2005) Enhancement of natural killer cells and increased survival of adult
mice fed daily Echinacea root extract from youth. Biogerontology 6: 157-163.
Miller, S.C. (2004) Echinacea in vivo: A prophylactic agent in normal mice and a therapeutic agent in
leukemic mice. In: Echinacea: The genus Echinacea (Medicinal and Aromatic Plants--Industrial Profiles (S.C. Miller, Editor). CRC Press, Boca Raton, FL, p. 153-162.
Miller, S.C. (2004) Two immunoenhancers are not better than one. In: Echinacea: The genus Echinacea (Medicinal and Aromatic Plants--Industrial Profiles (S.C. Miller, Editor). CRC Press, Boca Raton, FL, p. 219-230.
Currier, N.L., Lejtenyi, D. and Miller, S.C. (2003) The effect with time of administration in vivo, of the
polysaccharide, arabinogalactan, on the immune and hemopoietic cell lineages in murine spleen and bone marrow. Phytomedicine 10(2-3): 145-153.
Lejtenyi, D., Osmond, D.G. and Miller, S.C. (2003) Natural killer cells and B lymphocytes in L-selectin and
Mac-l/LF A-I knockout mice: Marker dependent but not cell lineage dependent changes in the spleen and bone marrow. Immunobiology 207: 129-135.
Currier, N.L. and Miller S.C. (2002) The effect of immunization with killed tumor cells, with/without feeding
of E.purpurea in an erythroleukemic mouse model. Journal of Alternative and Complementary Medicine. 8(1): 49-58.
Miller, S.C. (2002) Hemopoietic reconstitution of irradiated, stem cell injected mice: Dynamics of
restoration of various cell lineages of the spleen and bone marrow. Journal of Hematotherapy and Stem Cell Research 11(6): 965-970.
Currier, N.L. and Miller, S.C. (2001) TNF-a further augments natural killer cells when co-administered with
an interferon inducer to irradiated, leukemic, bone marrow-transplanted mice. Cancer Chemotherapy & Pharmacology 47(2): 185-188.
Currier, N.L. and Miller, S.C. (2001) E. purpurea and melatonin augment natural killer cells in leukemic
mice and prolong life span. Journal of Alternative and Complementary Medicine 7(3): 241-251.
Currier, N.L., Sicotte, M. and Miller, S.C. (2001) Deleterious influence of Echinacea purpurea and
melatonin on cells of the myeloid lineage in the spleen and bone marrow of mice. Journal of Leukocyte BioIogy 70: 274-277.
Currier, N.L. and Miller, S.C. (2000) Natural killer cells from aging mice treated with extracts from
Echinacea purpurea are quantitatively and functionally rejuvenated. Experimental Gerontology 35(5): 627-639.
Currier, N.L., Sun, L. Z-Y. and Miller, S.C. (2000) Exogenous melatonin: Quantitative enhancement in vivo of cells mediating non-specific immunity. Journal of Neuroimmunology 104:101-108.
Yu, Q., Miller, S.C. and Osmond, D.G. (2000) Melatonin inhibits apoptosis during early B cell
development in mouse bone marrow. Journal of Pineal Research 29: 86-93.
Sun, L.Z-Y., Currier, N.L. and Miller, S.C. (1999) The American coneflower: A prophylactic role involving
non-specific immunity. Journal of Alternative and Complementary Medicine 5 (5): 437-446.
Currier, N.L. and Miller, S.C. (1998) Influence of an interferon inducer on bone marrow transplant
reconstitution in irradiated, leukemic mice: Elevated natural killer cell numbers and improved life span. Nature Immunology 16: 6-17.
Mahoney, MX., Currier, N.L. and Miller, S.C. (1998) Natural killer cell levels in older mice are gender
dependent: Thyroxin is a gender independent natural killer cell stimulant. Nature Immunology 16:165-174.
Whyte, AL. and Miller, S.C. (1998) Strain differences in natural killer cell-mediated immunity among mice:
A possible mechanism for the low natural killer cell activity of A/Jmice. Immunobiology 199: 23-38.
Miller, S. C. and Kearney, S.L. (1997) Effect of in vivo administration of trans retinoic acid on the
hemopoietic cell populations of spleen and bone marrow: Profound strain differences between A/Jand C57Bl/6J mice. Laboratory Animal Science 48(1): 74-80.
Dussault, I. and Miller, S.C. (1996) The effect on leukemia cell numbers of in vivo administration of
immunotherapeutic agents is age dependent. Oncology 53: 241-246.
Dussault, I. and Miller, S.C. (1995) Effectiveness of immunotherapy in aged leukemic mice. Gerontology
Dussault, I. and Miller, S.C. (1995) Suppression of natural killer cell activity in infant mice occurs after
target cell binding. Nature Immunology 14: 35-43.
Giboda, M., Jacobs, P., Smith, J.M., and Miller, S.C. (1995) Immune response of mice infected with
Schistosoma mansoni is modulated by antifibrotic treatment. Annals of Tropical Medicine and Parasitology 89(4): 415-424.
Dussault, I. and Miller, SC. (1994) Decline in natural killer cell-mediated immunosurveillance in aged
mice: A consequence of reduced cell production and tumor binding capacity. Mechanisms of Ageing and Development 75: 115-129.
Miller, S.C. (1994) The development of natural killer (NK) cells from Thy-1 1o Lin- Sca-1+ stem cells:
Acquisition by NK cells of the homing receptor MEL-14 and the integrin Mac-I. Immunobiology 190: 385-398.
Dussault, I. and Miller, S.C. (1993) Stimulation of natural killer cell numbers but not function in leukemic
infant mice: A system primed in infancy allows survival in adulthood. Nature Immunology 12: 66-78.
Miller, S.C., Fleming, W.H., Zsebo, K.M. and Weissman, I.L. (1993) The in vivo effects of stem cell factor
on hemopoietic and natural killer lineage cells in murine spleen and bone marrow. Nature Immunology 12: 293-301.
Miller, S.C. (1992) Age-related differences in the effect of in vivo administration of indomethacin on
hemopoietic cell lineages of the spleen and bone marrow of mice. Experientia 48: 674-678.
Miller, S.C., Christopher, F.L. and Dussault, I. (1992) Population dynamics of natural killer cells and T
lymphocytes in murine spleen and bone marrow during the development of erythroleukemia: The effect of indomomethacin. Nature Immunology 11: 78-92.
Miller, S.C. and Shatz, A. (1991) Relationship between large and small tumor-binding cells in the spleen
and bone marrow. Natural Immunity and Cell Growth Regulation 10: 320-326.
Christopher, F.L. and Miller, S.C. (1991) Effects of low pathogen environment on natural killer cells of
normal and B lymphocyte-deficient mice. Natural Immunity and Cell Growth Regulation 10: 216-225.
Christopher, F.L., Dussault, I. and Miller, S.C. (1991) Population dynamics of natural killer cells in the
spleen and bone marrow of normal and leukemic mice during in vivo exposure to interleukin-2. Immunobiology 184: 37-59.
Miller, S.C. and Christopher, F.L. (1989) Altered production and renewal of natural killer cells in B
lymphocyte-deficient CBA/N mice. Natural Immunity and Cell Growth Regulation 8: 245-254.
Miller, S.C., Galley, D. and Nguyen, D. (1988) Inhibition of natural killer cell mediated lysis of tumor cells
by normal and regenerating bone marrow. Immunobiology 177:82-90.
Miller, S.C., Nguyen, D. and Bird, I. (1988) The effect of bearing tumors on the ability of mice to reject
bone marrow transplants. Scandinavian Journal of Immunology 27: 427-432.
Miller, S.C. and Poirier, L. (1988) Characteristics of cells mediating spontaneous resistance to bone
marrow allografts. Immunobiology 178: 191-202.
Nassiry, L. and Miller, S.C. (1987) Renewal of natural killer cells in mice having elevated natural killer cell
activity. Natural Immunity and Cell Growth Regulation 6: 250-259.
Miller, S.C. (1984) Life history of cells mediating natural resistance to tumor cells and bone marrow
transplants: The respective roles of cell lineage commitment and host environment in determining strain characteristics of natural resistance to foreign marrow grafts. American Journal of Anatomy. 170:367-376.
Miller, S.C. (1983) Genetically determined resistance to foreign bone marrow transplantation:
characteristics of the effector cells. Journal of Immunology 131: 92-97.
Miller, S.C. (1982) Production and renewal of murine natural killer cells in the spleen and bone marrow.
Journal of Immunology 129: 2282-2286.
Miller, S.C. (1981) Failure to demonstrate morphologically the presence of colostral or milk cells in the
wall of the gastrointestinal tract of the suckling neonatal mouse. Journal of Reproductive Immunology 3:187-194.
Miller, S.C. (1981) Genetic resistance to transplantation of xenogeneic bone marrow tin mice of various
strains: influence of an interferon inducer and age. Scandinavian Journal of Immunology 14: 515-532.
Kanamaru, A. Durban, E. Gallagher, M.T., Miller, S.C. and Trentin, J.J. (1980) Augmentation of erythroid
burst formation by the addition of thymocytes and other myelo-Iymphoid cells. Journal of Cell Physiology 104: 187-197.
Yang, W.C., Miller, S.C. and Osmond, D.G. (1978) Maturation of bone marrow lymphocytes. II.
Development of Fc and complement receptors and surface immunoglobulin studies by rosetting and radioautography. Journal of Experimental Medicine 148: 1251-1270.
Miller, S.C., Kaiserman, M. and Osmond, D.G. (1977) Small lymphocyte production and lymphoid cell
proliferation in mouse bone marrow. Experientia 134: 129-131.
Miller, S.C. and Osmond, D.G. (1976) Quantitative studies of lymphocytes and other cell populations in
the bone marrow of neonatally thymectomized mice. Anatomical Record 184: 325-333.
Miller, S.C. and Osmond, D.G. (1975) Lymphocyte populations in mouse bone marrow: quantitative kinetic studies in youn
Miller, S.C. and Osmond, D.G. (1974) Quantitative changes with age in bone marrow cell populations of
C3H mice. Experimental Hematology 2: 227-236.
Miller, S.C. and Osmond, D.G. (1973) The proliferation of lymphoid cells in guinea pig bone marrow. Cell
Osmond, D.G., Miller, S.C. and Yoshida, Y. (1973) Kinetic and hemopoietic properties of lymphoid cells in
the bone marrow. Haemopoietic Stem Cells. CIBA Foundation Symposium (Wolstenholme, G.E.W. and M. O'Connor, Editors) ASP, Elsevier/North Holland Press, Amsterdam, pp.131-156.
Protokoll der Krebssprechstunde vom 2.1.2005 mit dem Thema Adjuvante Therapie und Behandlung von Knochenmetastasen Deutsche Krebsgesellschaft e.V. Steinlestraße 6 60596 Frankfurt am Main Experte in dieser Sprechstunde Ludwig Maximilians UniGroßhadern München Frage: Ich hatte Ende 2002 Brustkrebs, dann Chemotherapie, Strahlenbehandlung und Tamoxifen. Ende 2004 wurden erne