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J. Ocean Univ. China (Oceanic and Coastal Sea Research) Review
DOI 10.1007/s11802-012-2109-1
ISSN 1672-5182, 2012 11 (4): 533-538
http://www.ouc.edu.cn/xbywb/
E-mail: [email protected]
Bromophenols from Marine Algae with Potential
Anti-Diabetic Activities
1) Department of Pharmacology, Capital Medical University, Beijing 100069, P. R. China 2) Institute of Oceanology, Chinese Academy of Science, Qingdao 266071, P. R. China (Received July 16, 2012; revised August 13, 2012; accepted September 17, 2012) Ocean University of China, Science Press and Spring-Verlag Berlin Heidelberg 2012 Abstract Marine algae contain various bromophenols with a variety of biological activities, including antim-
icrobial, anticancer, and anti-diabetic effects. Here, we briefly review the recent progress in researches on the biomaterials from marine algae, emphasizing the relationship between the structure and the potential anti-diabetic applications. Bromophenols from marine algae display their hyperglycemic effects by inhibiting the activities of protein tyrosine phosphatase 1B, α-glucosidase, as well as other mechanisms. Key words bromophenols; marine algae; type 2 diabetes mellitus
* Corresponding authors. Tel.: 0086-532-82898916 E-mail: [email protected]; [email protected] References
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