Läkemedelsföretagen tvekar ofta inför att satsa på ny antibiotika för att det inte är tillräckligt lönsamt, men de ska nu ges ekonomiska morötter köpa inderal receptfritt Ofta fås en bättre/snabbare absorption när läkemedel tas på fastande mage men för vissa läkemedel är det önskvärt att minska risken för biverkningar från mag-tarmkanalen genom att läkemedlet tas tillsammans med föda.
Microsoft word - publikationsliste.doc
PUBLIKATIONEN ORIGINALARBEITEN Wei-Min Tong, Enikö Kallay, Harald Hofer, Wolfgang Hulla, Theresa Manhardt, Meinrad Peterlik and Heide S. Cross. Growth regulation of human colon cancer cells by epidermal growth
factor and 1,25-dihydroxyvitamin D3 is mediated by mutual modulation of receptor expression. Eu J Wei-Min Tong, Harald Hofer, Meinrad Peterlik, Heide S. Cross. Mechanism of antimitogenic
action of Vitamin D in Human Colon Carcinoma Cells: Relevance for Suppression of Epidermal
Growth Factor stimulated Cell Growth. Oncology Research 1999; 11, (2): 77-84. Harald Hofer, Guan-Min Ho, Meinrad Peterlik, Milan R. Uskokovic, Jae Kyoo Lee, M Christina White, Gary H. Posner, and Heide S. Cross. Biological effects of 1alpha-hydroxy- and 1beta-
(hydroxymethyl)-vitamin D compounds relevant for potential colorectal cancer therapy. J Pharm Exp Heide S. Cross, Petra Bareis, Harald Hofer, Martin G Bischof, Erika Bajna, Stefan Kriwanek, Elisabeth Bonner; Meinrad Peterlik. 25- Hydroxyvitamin D3-1-alpha-hydroxylase and vitamin D
receptor gene expression in human colonic mucosa is elevated during early cancerogenesis.
Petra Bareis, Martin G. Bischof, Givanna Bises, Harald Hofer, Christian Pötzi, Teresa Manhardt, Rosemary Bland, Heide S. Cross. Clonal differences in expression of 25-
hydroxyvitamin D3-1 -hydroxylase, of 25-hydroxyvitamin D3-24-hydroxylase and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1a,25-dihydroxyvitamin D3 Exp Cell Res. 2002,10;276(2):320-7.Wolfgang Jessner, Michael Gschwandtler, Petra Steindl-Munda, Harald Hofer, Thomas Watkins, Friedrich Wrba, Christian Müller, Alfred Gangl, Peter Ferenci A pilot study on primary
interferon resistance as predictor of non response to treatment in chronic hepatitis virus genotype 1
infection.Lancet. 2001,13;358(9289):1241-2.
Peter Ferenci, Harald Brunner, Karin Nachbaur, Christian Datz, Michael Gschwandtler, Harald Hofer, Petra Steindl-Munda, Wolfgang Vogel Combination of interferon induction therapy and
ribavirin in chronic hepatitis c.Hepatology. 2001;34(5):1006-11.Harald Hofer, Hans C Bankl, Friedrich Wrba, Petra Steindl-Munda, Markus Peck- Radosavljevic, Christoph Österreicher, Christian Mueller, Alfred Gangl, Peter Ferenci
Hepatocellular fat accumulation in patients with chronic hepatitis C due to genotype 3a - role of
impaired cholesterol synthesis, Am J Gastroenterol. 2002;97(11):2880-5.
Markus Peck-Radosavljevic, Martina Wichlas, Monika Homoncik-Kraml, Anna Kreil, Harald Hofer, Wolfgang Jessner, Alfred Gangl, Peter Ferenci Rapid suppression of Hematopoiesis by
standard or pegylated Interferon. Gastroenterology. 2002;123(1):141-51.
Kramer L, Bauer E, Funk G, Hofer H, Jessner W, Steindl-Munda P, Wrba F, Madl C, Gangl A, Ferenci P. Subclinical impairment of brain function in chronic hepatitis C infection. J Hepatol Harald Hofer, Thomas Watkins-Riedel, Oskar Janata, Edward Penner, Heidemarie Holzmann, Petra Steindl-Munda, Alfred Gangl, Peter Ferenci Spontaneous viral clearance in patients with
acute hepatitis C can be predicted by repeated measurements of serum viral load, Hepatology.
Jessner W, Stauber R, Hackl F, Datz C, Watkins-Riedel T, Hofer H, Gangl A, Kessler H, Ferenci P. Early viral kinetics on treatment with pegylated interferon-alpha-2a in chronic hepatitis C
virus genotype 1 infection. J Viral Hepat 2003;10(1):37-42
Harald Hofer, Fritz Wrba, Christoph Österreicher, Alfred Gangl, Peter Ferenci, Edward Penner
Centrilobular necrosis in autoimmune hepatitis: A histological feature associated with an acute onset
Steindl-Munda P, Ferenci P, Brunner H, Nachbaur K, Datz C, Gschwantler M, Hofer H, Stauber R, Hackl F, Jessner W, Rosenbeiger M, Gangl A, Vogel W; Austrian Hepatitis Study Group.
Impact of high-dose interferon induction and ribavirin therapy in patients with chronic hepatitis C
relapsing after or not responding to interferon monotherapy. Liver Int. 2003 Aug;23(4):269-75.
Stauber, R., E., Hofer, H., Hackl, F., Schütze, K., Datz, C., Hegenbarth, K., Jessner, W., Steindl- Munda, P., Ferenci, P.,for the Austrian Hepatitis Study Group Retreatment of patients with
chronic hepatitis C not responding to interferon/ribavirin combination therapy with daily interferon
plus ribavirin plus amantadine. Wiener Klin Wochenschrift 2004; 116
Harald Hofer, Christoph Österreicher, Wolfgang Jessner, Melitta Penz, Petra Steindl-Munda, Friedrich Wrba, Peter Ferenci. Hepatic iron concentration does not predict response to standard
and pegylated-IFN/ribavirin therapy in patients with chronic hepatitis C. J Hep 2004 40(6):1018-1022Harald Hofer, Julius Benjamin Neufeld, Christoph Oesterreicher, Paul Grundtner, Fritz Wrba, Alfred Gangl, Peter Ferenci, and Christoph Gasche. Bi-allelic presence of the interleukin-10
receptor 1 G330R allele is associated with cirrhosis in chronic HCV-1 infection Genes Immun.
Osterreicher CH, Datz C, Stickel F, Hellerbrand C, Penz M, Hofer H, Wrba F, Penner E, Schuppan D, Ferenci P. Association of myeloperoxidase promotor polymorphism with cirrhosis in
patients with hereditary hemochromatosis. J Hepatol. 2005 Jun;42(6):914-9. Epub 2005 Apr 2.
Osterreicher CH, Datz C, Stickel F, Hellerbrand C, Penz M, Hofer H, Wrba F, Penner E, Schuppan D, Ferenci P. TGF-beta1 codon 25 gene polymorphism is associated with cirrhosis in
patients with hereditary hemochromatosis. Cytokine. 2005 Jul 21;31(2):142-8.
Kramer L, Hofer H, Bauer E, Funk G, Formann E, Steindl-Munda P, Ferenci P. Relative impact
of fatigue and subclinical cognitive brain dysfunction on health-related quality of life in chronic
hepatitis C infection. AIDS. 2005;19, S3:S85-92.
Formann E, Steindl-Munda P, Hofer H, Jessner W, Bergholz U, Gurguta C, Ferenci P. Long-
term follow-up of chronic hepatitis C patients with sustained virological response to various forms of
interferon-based anti-viral therapy. Aliment Pharmacol Ther. 2006 Feb 15;23(4):507-11.
Hofer H, Oesterreicher C, Wrba F, Ferenci P, Penner E. Centrilobular necrosis in autoimmune
hepatitis: a histological feature associated with acute clinical presentation. J Clin Pathol. 2006
Hofer H, Gurguta C, Bergholz U, Steindl-Munda P, Ferenci P. Standard interferon-alpha in
combination with ribavirin for hepatitis C patients with advanced liver disease and thrombocytopenia.
Wien Klin Wochenschr. 2006;118(19-20):595-600.
Scherzer TM, Staufer K, Hofer H, Novacek G, Ferenci P, Vogelsang H Efficacy and safety of
antiviral therapy in patients with crohn´s disease and chronic hepatitis C. Aliment Pharm Therapeut
Scherzer TM, Rajender KR, Staufer K, Hofer H, Steindl-Munda P, Ferenci F. Hepatocellular
carcinoma in long-term sustained virologic responders to antiviral treatment for chronic hepatitis C.
Elke M. Hennes, Mikio Zeniya , Albert. J. Czaja , Albert Parés , George N. Dalekos , Edward L. Krawitt , Paulo L. Bittencourt , Gilda Porta , Kirsten M. Boberg , Harald Hofer , Francesco B. Bianchi , Minoru Shibata , Christoph Schramm , Barbara Eisenmann de Torres , Peter R. Galle, Ian McFarlane ,Hans-Peter Dienes , Ansgar W. Lohse The International Autoimmune
Hepatitis Group Simplified criteria for the diagnosis of autoimmune hepatitis, Hepatology 2008 in
Peter Ferenci, Harald Brunner, Hermann Laferl, Thomas-Matthias Scherzer, Andreas Maieron, Michael Strasser, Gabriele Fischer, Harald Hofer, Martin Bischof, Rudolf Stauber, Michael Gschwantler, Petra Steindl-Munda, Karin Löschenberger for the Austrian Hepatitis Study Group A Randomized, Prospective Trial of Ribavirin 400 mg/day versus 800 mg/day in Combination
with Peginterferon alfa-2a for Chronic Hepatitis C Genotypes 2 and 3 Hepatology 2008 in press
II) BUCHBEITRÄGE & KONSENSUSREPORTS
H.S. Cross, W.-M. Tong, H. Hofer, Y. Sheinin, M. Peterlik. The intrinsic 1,25(OH)2D3/VDR system of human colonic epithelial cells: Upregulation during tumor progression. IN: Vitamin D Chemistry, Biology and Clinical Applications of the Steroid Hormone. Eds.; Norman AW, Bouillon R, Thomasset M, University of California, Riverside, pp 495-497, 1997
Heide S. Cross, Harald Hofer, Petra Bareis, Giovanna Bises, Gary H. Posner, Meinrad Peterlik.
Vitamin D Compounds and colorectal cancer: A rationale for their use in prevention and therapy.
Proceedings of the tenth workshop of vitamin D, May 2000 Harald Hofer, Therapie der akuten Hepatitis C. In: Leitfaden der Infektionskrankheiten der Leber, Hofer H, Penner E. Diagnose, Klassifikation und Therapie der Autoimmunhepatitis und Overlap Hofer H. Therapie der akuten Hepatitis B. Konsensus der ÖGGH zur Diagnostik und Therapie der
Services available at Roscommon County Hospital INTRODUCTION This paper has been prepared following a request from the Oireachtas members for a briefing regarding the on going service changes at Roscommon County Hospital due to the reconfiguration of the Emergency Department at the hospital on the 11th July 2011. CONTEXT OF RECENT CHANGES TO SERVICES: The changes to service delivery in
Gaceta Bibliográficade Atención Primaria ANÁLISIS DE LAS REUNIONES ENTRE LOS MÉDICOS DE CA- formación imparcial. Aunque los médicos de cabecera pueden percibir estas reuniones y el BECERA Y LOS REPRESENTANTES DE LAS COMPAÑÍAS FAR- apoyo a la formación continuada ofrecido por los laboratorios como beneficioso, la industria considera que son una vía coste-efectiva para aumentar la p