S A F E T Y D A T A S H E E T C A F FE IN E C IT R A T E 1 . I D E N T I FI C A T I O N O F T H E S U B ST A N C E /P R E P A R A T I O N A N D T H E C O M P A N Y : P R O D U C T N A M E : C H EM I C A L N A M E 2 :
1,3,7-Trimethyl-1,2,6-tetrahydropurine, 2-hydroxy-1,2,3-propantricarbonic acid (1:1)
P A R T N o .: S U P P L IE R :
J M Loveridge plcSouthbrook Road, SouthamptonHampshireSO15 1BHTel: 023 8022 2008Fax: 023 8022 2117
2 . C O M P O S IT IO N /I N F O R M A T I O N O N IN G R E D I E N T S : 3 . H A Z A R D S ID E N T IF I C A T I O N :
Harmful by inhalation and if swallowed. Risk of serious damage to eyes. 4 . F I R S T A ID M E A S U R E S : G E N E R A L :
IN ALL CASES OF DOUBT OR WHEN SYMPTOMS PERSIST, ALWAYS SEEKMEDICAL ATTENTION
IN H A LA T IO N :
Move affected person to fresh air.If recovery not rapid, seek medical attention. IN G E ST I O N :
DO NOT INDUCE VOMITING. In case of spontaneous vomiting, be sure that vomitcan freely drain because of danger of suffocation. Only when conscious, rinse mouthwith plenty of water and give plenty of water to drink - (approx 500ml). Keep patient atrest and obtain medical attention.
Remove contaminated clothing. Wash affected area with plenty of soap and water. Ifirritation persists, seek medical attention. Launder clothing before re-use.
Promptly wash eyes with plenty of water while lifting the eye lids. Continue to rinse forat least 15 minutes and get medical attention. 5 . F I R E FI G H T I N G M E A S U R E S : E X T IN G U IS H IN G M E D I A :
Water spray, foam, dry powder or carbon dioxide. 1 03 51 - C AF FE IN E C IT RA T ES P EC IA L F IR E F I G H T IN G
Take measures to retain water used for extinguishing. Do not release contaminated
P R O C E D U R E S :
water into drains, soil and surface water. Dispose of contaminated water and soilaccording to local regulations. U N U S U A L F IR E & E X P L O S IO N
Finely divided material can cause dust explosion. H A ZA R D S: H A ZA R D O U S C O M B U ST I O N
Burning may release oxides of carbon and other hazardous gases or vapours. P R O D U C T S: P R O TE C T IV E M E A SU R E S I N F I R E :
Fire fighters should wear self-contained breathing apparatus. 6 . A C C I D E N T A L R E L E A S E M E A S U R E S: P E R S O N A L P R E C A U TI O N I N S P IL L :
Avoid direct contact with skin, eyes and clothing. Wear appropriate protective clothing. P R EC A U T IO N S T O P R O TE C T
Prevent contamination of soil, drains and surface water. E N V IR O N M E N T: S P IL L C L E A N U P M E T H O D S:
Cover spillage with damp inert material, take-up or collect and place into a suitableclosable labelled container for disposal. Avoid dry sweeping or other methods whichraise dust. Wash the area clean with water and detergent, observing environmentalrequirements. 7 . H A N D L I N G A N D S T O R A G E : U S A G E P R E C A U T IO N S :
HANDLING - Product should be used in accordance with good industrial principles forhandling and storing of hazardous chemicals. Avoid creating or raising dust. Avoid contact with skin or eyes. S TO R A G E P R E C A U T IO N S :
Store in a cool, dry, well ventilated place, in securely closed original container. 8 . E X PO S U R E C O N T R O L S A N D P E R S O N A L PR O T E C T I O N : IN G R ED IE N T C O M M E N T S :
No specific OES assigned, however for dusts of any kind, ensure LTEL (8-hour TWAref. period) level does not exceed 10 mg.m3 for total inhalable dust or 4 mg.m3 forrespirable dust (or) as recommended in current edition of EH40. V E N TI L A T I O N :
Provide adequate general and local exhaust ventilation. R E S P IR A T O R S:
If unable to control dust emissions below OES limits, an approved dust protection to P2level of protection is recommended. P R O TE C T IV E G L O V ES : E Y E P R O T EC T IO N :
Wear approved chemical safety goggles where eye exposure is reasonably probable. O T H E R P R O T E C T IO N :
Use engineering controls to reduce air contamination to permissible exposure level. H Y G IE N IC W O R K P R A C T IC E S:
SKIN PROTECTION - apply barrier cream to hands and exposed skin. Regularly vacuum dust to minimise the potential of air-borne exposure. 9 . P H Y S I C A L A N D C H E M I C A L PR O P E R T I E S : A P P EA R A N C E : 1 03 51 - C AF FE IN E C IT RA T EO D O U R /T A S T E:
Odourless or no characteristic odour. P H Y SI C A L D A T A C O M M E N TS :
Fine dust may create explosive mixture with air. Dust explosion hazard ST2. M E L T ./ F R E E Z . P O I N T (° C , in te rva l ): D E N SI T Y /S P E C I F IC G R A V I TY (g/ m l): T em pera tu re (°C ): p H -V A L U E, D IL U TE D SO L U TI O N : C o n cen tra ti o n % M : S O L U B IL I TY D E S C R IP T I O N : S O L U B IL I TY V A LU E (g/ 1 00 g H 2 O 1 0 . S T A B I L I T Y A N D R E A C T I V I T Y : S TA B IL I TY :
Stable under normal conditions of use. H A ZA R D O U S D E C O M P . P R O D U C TS :
Thermal decomposition or burning may release oxides of carbon and oxides of nitrogen. 1 1 . T O X I C O L O G I C A L I N F O R M A T I O N : T O X I C D O SE - L D 5 0 : H E A L T H H A ZA R D S, G E N ER A L :
Irritating to eyes or if inhaled as dust.
No irritant effect or sensitising effect. 1 2 . E C O L O G IC A L IN FO R M A T IO N : E C O L O G IC A L IN F O R M A T IO N :
No specific information available, but material is expected to have adverse effect on theenvironment. W A T E R H A ZA R D C L A SS IF I C A T IO N : 1 3 . D IS P O S A L C O N S I D E R A T I O N S : D I S P O SA L M E T H O D S:
This material and/or its container must be disposed of as hazardous waste according toSpecial Waste Regulations 1996 or according to local regulations, in compliance withDuty of Care Regulations and Special Waste Regulations. W A S T E C L A S S:
WASTE CODE: 0705** HAZARDOUS PROPERTY: H6
1 4 . T R A N SP O R T I N F O R M A T I O N : 1 03 51 - C AF FE IN E C IT RA T EG E N E R A L :
Not classified as hazardous for transport. 1 5 . R E G U L A T O R Y IN F O R M A T I O N : LABEL FOR SUPPLY: R I S K P H R A SE S :
R-20/22 Harmful by inhalation and if swallowed. R-41 Risk of serious damage to eyes.
S A F E T Y P H R A S E S:
S-26 In case of contact with eyes, rinse immediately with plenty of water and seekmedical advice. S-39 Wear eye/face protection. S-46 If swallowed seek medical advice immediately and show this container label.
U K R E G U L A T O R Y R E F E R E N C E S:
The Control of Substances Hazardous to Health Regulations 1988. Chemicals (HazardInformation & Packaging) Regulations 1993. Classification, Packaging and LabellingRegulations 1984. 1 6 . O T H E R I N F O R M A T I O N : IN F O R M A T IO N SO U R C E S:
This product has been classified in accordance with CHIP3 regulations. R E V IS IO N C O M M E N TS : IS S U E D B Y : D I S C L A I M E R :
The foregoing data has been compiled for safety information only and does not formpart of any selling specification. Information contained in this Data Sheet is to the bestof JMLs knowledge correct at the time of publication. Customers should always satisfythemselves, that the product which they have selected is entirely suitable for theirpurpose under their conditions of use and in compliance with current regulations. Forany further information, please contact the supplier.
FOR IMMEDIATE RELEASE Media Contact: Dan Budwick Pure Communications (973) 271-6085 Warp Drive Bio Appoints Co-Founder Gregory Verdine, Ph.D., to Chief Executive Officer; Expands Team with Two Key Appointments James Nichols, Ph.D., Appointed to Chief Operating Officer; Julian Adams, Ph.D., Joins Board of Directors Cambridge, Mass. – July 2, 2013 - Warp Drive Bio, a lif
Guidelines for the Management of Patients on the Ketogenic Diet Introduction The ketogenic diet (KD) is an established, effective nonpharmacologic treatment for intractable childhood epilepsy (Freeman et al., 2007). It is a high fat, restricted carbohydrate regimen that was first used to treat epilepsy in the 1920s (Wilder RM, 1921). It was observed that fasting decreased seizure