MISOPROSTOL AND INDUCED ABORTION IN ACCRA, GHANA
Maya, Ernest Tei1; Mumuni, Kareem2; Samba, Ali 2;
Organizations: 1: Ridge Regional Hospital, Accra ,
Ghana; 2: Korle-bu Teaching Hospital, Accra, Ghana; 3:
School of Public Health UG, Accra, Ghana
• Unsafe abortion contributes significantly towards
maternal morbidity and mortality in Ghana
• Autopsy reports have revealed that abortion
related causes are the leading cause of maternal
• Misoprostol is seen as an important medication
in obstetric practice and making it easily available
for use is seen as one of the most important
measures to reduce maternal mortality in sub-
• Misoprostol however has been blamed for the
increase in global incidence of unsafe abortion because of its low cost, convenience of use and lesser traumatic consequences
• The abortion law in Ghana is less restrictive
and safe abortion is provided in some public health institutions
• However, self induced abortion is common and
anecdotal information indicates that the availability of misoprostol is mostly responsible for this
• This study aims to determine the proportion of
women presenting with incomplete abortion who have induced abortion, proportion who used misoprostol, sources of misoprostol and what information is given to these women
• A cross-sectional survey was undertaken
consecutively enrolled women presenting with
incomplete abortion for MVA at the Ridge Regional
Hospital from 1st July 2010 to 30th August 2010
characteristics, contraceptive practices at the time of
the pregnancy, whether abortion was spontaneous
or induced, type and source of abortifacients, route
• Descriptive statistics were estimated using
• Bivariate analysis was performed using Chi-
square tests and Student’s t tests (with significance level at 0.05).
– 35% (48) reported having had induced abortion
– Mean age of all respondents = 26.8yrs (SD 6.1)
– Mean age spontaneous abortion= 28.7yrs (SD 6.1)
– Mean age induced abortion = 23.4yrs (S.D 4.4)
– Mean age misoprostol = 22.3yrs (S.D 4.4)
– 41% nulliparous – Gestational ages of the pregnancies : 1 - 6 months
• Of the 48 cases, 95.8% had procured the
abortifacients by themselves /by others and self induced the abortion
• 4.2% had either a D&C or intramuscular
• 91.7% (44) reported they did not want the
pregnancy out of which 84.1% were not on contraception at the time of the pregnancy
Abortifacients/proced Frequency Percentage
• Drug stores/pharmacies supplied 97.4% of
• No. of tablets used: 2 to 8 (median - 4)
induced abortion was significantly associated with misoprostol use (p< 0.001)
• Both the oral and rectal routes were used by
• Only 5.3% (2/38) were told to expect some
• No other information about the abortion
process and where to seek help if need be was given
• About a third of cases with incomplete
abortion presenting for MVA had induced abortion
• Self induced abortion is very high among
• Misoprostol reportedly is the commonest
abortifacient used by patients with induced abortion
• Drug stores/pharmacies are the major
• Virtually no information on the abortion
process, side effects of misoprostol and where to seek treatment in case of complications was given to clients
• There is the need for the health authorities to
educate the populace on the benefits of contraceptive use, dangers of unsafe abortion and therefore the need to use safe abortion services when induced abortion is desired
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Publikasjonsliste for professor Adrian Smith, dr.med.vet., dipl. ECLAM, MA, VetMB, MRCVS Doktorgrader: 1) Avhandling for graden dr. scient. ved Norges veterinærhøgskole: Aspects of seasonal breeding in the male blue fox (Alopex lagopus): some testicular parameters and plasma hormone concentrations. 75 sider. 1984. 2) Avhandling for graden dr. med. vet. ved Norges veterin�