Columbinerx.com

Material Safety Data Sheet
For Compliance with OSHA 29 CFR 1910.1200 and ANSI Z400.1-1998
Section I. Product and Company Identification
Product Name
Item Code
Commercial Name
Decadron phosphate, Decdan, Dexacort, Dexadreson, Dexagro, Megacort, Soldesam, Solu-Decadron, Spersadox, Turbinaire Synonym(s)
*Fluoro-9-trihydroxy-11,17,21-methyl-16-pregnadiene-1 sodiumphosphate* Disodium dexmethasone phosphate* Dexamethasone disodium phosphate* Sodium CHEMTREC (24hr) 1-800-424-9300
HMIS Label
Supplier
Health Hazard
1 - Slight
Flammability
1 - Slight
Physical Hazard
0 - Minimal
Personal Protection
Section II. Composition and Information on Ingredients
% by Weight
LC50/LD50
ORAL (LD50): Acute: 1800 mf/kf [Mouse].
Section III. Hazards Identification
Potential Acute Health
Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation.
Potential Chronic
CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC Health Effects
EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female [POSSIBLE]. Repeated or prolonged exposure is not known to aggravate medical condition.
Section IV. First Aid Measures
Eye Contact
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
Skin Contact
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used.
Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
Section V. Fire and Explosion Data
Flash Points
Flammable Limits
May be combustible at high temperature.
Products of
These products are carbon oxides (CO, CO2), Halogenated compounds, phosphates. Some metallic oxides.
Combustion
Fire Hazards
Slightly flammable to flammable in presence of heat. Non-flammable in presence of shocks. As with most organic solids, fire is possible at elevated temperatures.
Explosion Hazards
Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks. Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Fire Fighting Media
SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam.
and Instructions
Material Safety Data Sheet
For Compliance with OSHA 29 CFR 1910.1200 and ANSI Z400.1-1998
Extinguishing Media to
Section VI. Accidental Release Measures
Spill Cleanup
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish Instructions
cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.
Section VII. Handling and Storage
Handling and Storage
Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 8 C (46.4 F). Refrigerate. Precautions: Keep away from heat. Keep away from sources of ignition. Do not ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or label.
Section VIII. Exposure Controls/Personal Protection
Personal Protection
Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Other Protective
Engineering Controls: Use process enclosures, local ventilation or other engineering controls to keep airborne Measures and
levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to Equipment
keep exposure to airborne contaminants below the exposure limit.
Exposure Limits
Section IX. Physical and Chemical Properties
Appearance
solid. (Crystalline powder.) White to Yellowish in color.
Molecular Weight
Boiling Point
Melting Point
Specific Gravity
Vapor Pressure
Vapor Density
Viscosity
Solubility
Section X. Stability and Reactivity Data
Stability
Conditions to Avoid
Conditions of Instability: Excess heat, incompatible materials, dust generation.
Materials to Avoid
Polymerization will not occur. Hygroscopic; Keep container tightly closed.
Section XI. Toxicological Information
Routes of Entry
Toxicity Data
Acute oral toxicity (LD50): 1800 mg/kg [Mouse]. May cause adverse reproductive effects and birth defects (teratogenic).
Material Safety Data Sheet
For Compliance with OSHA 29 CFR 1910.1200 and ANSI Z400.1-1998
Section XII. Ecological Information
Information
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long-term degradation products may arise. Toxicity of the Products of Biodegradation: The products of degradation are as toxic as the product itself.
Section XIII. Disposal Considerations
Waste Disposal
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section XIV. Transport Information
DOT Classification
Not a DOT controlled material (United States).
Section XV. Other Regulatory Information
Regulations
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances. WHMIS (Canada): Not controlled under WHMIS (Canada). DSCL (EEC): R 40- Possible risks of irreversible effects. R 62- Possible risk of impaired fertility. S 2- keep out of reach of children. S 36/ 37- Wear suitable protective clothing and gloves.
Section XVI. Other Information

Source: http://columbinerx.com/pdfs/MSDS_Dexamethasone_Sod_Phos.pdf