Compchart for print v1.3 final.xls

Thames Valley Y-Site Intravenous Drugs Compatibility Chart (November 2005)
Prepared by the Thames Valley Critical Care Network Pharmacists Group* Note:
This table can be used for Y-site compatibility at the usual manufacturers concentrations. You should also ensure that the drugs checked are compatible in terms of carrier fluid

This table gives information for two drug combinations only . It can not be extrapolated to three drug combinations
Use of higher than the manufacturers recommended concentrations (eg in fluid restriction) may affect compatibility
The majority of sources cited define compatibility by physical compatibility rather than chemical compatibility
This table is a guide only. Full information can be obtained from your pharmacy department

Acetylcysteine
References
Adrenaline 9
Adrenaline
1 Compatible (Reference 1)
1 "Pocket Guide to Injectable Drugs" 11th Edition, Lawrence Trissel, 2001. Alfentanil 9
Alfentanil
American Society of Health System Pharmacists (ISBN 1-58528-023-2) Aminophylline 9
Aminophylline
2 "King Guide to Parenteral Admixtures: Compatibility of Critical Care Admixtures 2005", Amiodarone 9
Amiodarone
Patrick Catania, 2005. School of Pharmacy, University of the Pacific (www.kingguide.com) Aprotinin 9
Aprotinin
Atracurium 9
Atracurium
4 Parvolex Injection, ABPI Medicines Compendium 2005, p1840-1841 (ISBN 0-0907102-23-9) Calcium Chloride
Calcium Chloride
5 Rapifen Intensive Care, ABPI Medicines Compendium 2005, p2024-2025 (ISBN 0-0907102-23-9) Calcium Gluconate
Calcium Gluconate
6 Cordarone X Intravenous, ABPI Medicines Compendium 2005, p547-548 (ISBN 0-0907102-23-9) Ciprofloxacin
Ciprofloxacin
7 Tracrium Injection, ABPI Medicines Compendium 2005, p2417-2418 (ISBN 0-0907102-23-9) Cisatracurium
Cisatracurium
8 Nimbex Forte Injection, Nimbex Injection 2mg/ml , ABPI Medicines Compendium 2005, p1699-1703 (ISBN 0-0907102-23-9) Clonidine 9
Clonidine
9 Catapress Ampoules, ABPI Medicines Compendium 2005, p411-412 (ISBN 0-0907102-23-9) Compound Sodium Lactate Solution (Hartmann's)
Compound Sodium Lactate Solution (Hartmann's)
10 Dopacard, ABPI Medicines Compendium 2005, p721 (ISBN 0-0907102-23-9) Disodium Hydrogen Phosphate
Disodium Hydrogen Phosphate
11 Xigris, ABPI Medicines Compendium 2005, p2655-2657 (ISBN 0-0907102-23-9) Dobutamine 9
Dobutamine
12 Ventolin Injection, ABPI Medicines Compendium 2005, p2537-2538 (ISBN 0-0907102-23-9) Dopamine 9
Dopamine
13 Flagyl Injection (100ml), ABPI Medicines Compendium 2005, p935-936 (ISBN 0-0907102-23-9) Dopexamine 9
Dopexamine
14 Losec IV Infusion, ABPI Medicines Compendium 2005, p1403-1404 (ISBN 0-0907102-23-9) Drotrecogin Alfa (Activated)
Drotrecogin Alfa (Activated)
15 Diprivan 1%, Diprivan 2%, ABPI Medicines Compendium 2005, p697-701 (ISBN 0-0907102-23-9) Esmolol 9
16 Ultiva Injection, ABPI Medicines Compendium 2005, p2483-2487 (ISBN 0-0907102-23-9) Fentanyl 9
Fentanyl
17 "Physical and chemical compatibility of drotrecogin alfa (activated) with 34 drugs during simulated Y-site administration" Furosemide 9
Furosemide
HY Mann, SL Demmon, DA Boelk et al, Am J Health-Syst Pharm 2004; 61: 2664-2671 Gentamicin
Gentamicin
18 "John Farman intensive care unit compatibility chart", Cambridge University Hospitals NHS Foundation Trust, Glucose 4%, Sodium Chloride 0.18%
Glucose 4%, Sodium Chloride 0.18%
Pharmacy Department, In-house data generated by Brit Cadman and Tim House Glucose 5% 9
Glucose 5%
19 AstraZeneca, Personal communication (16/03/2005) Glyceryl Trinitrate (GTN) 2
Glyceryl Trinitrate (GTN)
20 Bayer, Personal communication (16/03/2005) Heparin (Sodium) 9
Heparin (Sodium)
21 Zeneus Pharma, Personal communication (22/03/2005) Insulin (Soluble) 9
Insulin (Soluble)
22 "Handbook on injectible drugs" 13th Edition, LA Trissel, 2005.
Isosorbide Dinitrate 9
Isosorbide Dinitrate
American Society of Health System Pharmacists (ISBN 1-58528-107-7) Labetalol 9
Labetalol
23 Schwartz Pharma, Personal communication (22/03/2005) Magnesium Sulphate
Magnesium Sulphate
24 Akzo Nobel, Personal communication (16/03/2005) Mannitol
Mannitol
Metronidazole
Metronidazole
Midazolam 9
Midazolam
Milrinone
Milrinone
Morphine 9
Morphine
Noradrenaline 9
Noradrenaline
Omeprazole 9
Omeprazole
Potassium Chloride v
Potassium Chloride
Potassium Phosphate
Potassium Phosphate
Propofol
Propofol
Remifentanil 9
Remifentanil
Rocuronium 9
Rocuronium
Salbutamol
Salbutamol
Sodium Bicarbonate
Sodium Bicarbonate
Sodium Chloride 0.9% 9
Sodium Chloride 0.9%
Sodium Nitroprusside 2
Sodium Nitroprusside
Thiopental
Thiopental
Vancomycin
Vancomycin
Vasopressin (Arginine Vasopressin)
Vasopressin (Arginine Vasopressin)
Vecuronium 9
Vecuronium
*Thames Valley Critical Care Network Pharmacists Group
John Radcliffe Hospital, Dep. Chief P'cists Rep John Radcliffe Hospital, (AICU), Chair (16/01/2004) John Radcliffe Hospital, Chief Pharmacists Rep Secretarial support was provided by Sue Gurney Data Input By: Sue Gurney, Mark Borthwick 2005, Thames Valley Critical Care Network Pharmacists Group Chart Approved By: Thames Valley Critical Care Network Pharmacists Group, 10 November 2005

Source: http://www.cc3n.org.uk/download/i/mark_dl/u/4012004675/4595430903/Compatibility%20Chart%20V1.3.pdf

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