GCRM-BELFAST: Clinical Manual: INF-Clin010-20131230 Page 1 of 1
GCRM-BELFAST, Excessive hair growth
cycle (day 1 is the first day of your period),
Edgewater House, Edgewater Road,
The first cycle should normally be monitored
Belfast, BT3 9JQ.
2) Remove unwanted hair by cosmetic measures,
by ultrasound scan, and you can also have
including shaving, waxing, depilation creams,
progesterone levels checked in the second
half of your cycle. If you do not ovulate, the
POLYCYSTIC OVARY SYNDROME
3) The combined oral contraceptive pill.
dose can be increased to 100mg/day or 150
Patient information sheet
mg/day. The pregnancy rate (per cycle) with
Polycystic ovary syndrome (PCOS) is a common
6) Vaniqa cream applied twice daily for at least 8
pregnancy rate is 8-10%.Clomifene should
weeks. You might need to use for at least 4
a) Irregular and infrequent periods, and failure to
ovulate (produce an egg). This may lead to
3) Metformin 500mg three times daily. This can
Because of the way hair grows, it can take at least
make you ovulate more frequently, though it
nine months to see the full benefit of certain
is not usually as as clomifene. It should be
taken as above (see excessive hair growth)
You may have some of these problems, and often
and the multiple pregnancy rate is only 1%.
To minimise any potential tummy upset with
other female members of your extended family may
Unlike clomifene, there is no time restriction
Metformin, take 500mg with your evening meal for 2
on how long it can be used. Metformin can
weeks, then 500mg with lunch and dinner for 2
weeks and then 500mg with breakfast, lunch and
above), so it may be beneficial to take both
The diagnosis of PCOS can be confirmed by an
ultrasound scan of your ovaries and by measuring
some of the reproductive hormones in your blood.
Irregular periods
The doctor will be able to tell you more about these
This is a surgical approach in which a small
Management of PCOS
3) Twelve days of a tablet such as Norethisterone
5) Ovulation Induction with Intra-uterine
What you do about PCOS depends on your needs.
If you are overweight, sustained weight loss is the
This is a specialised treatment and you will
Unfortunately (2) and (3) may cause weight gain, so
best way to reduce all the symptoms. When exercise
need to be seen by an infertility specialist to
it is important to try and exercise as much as
is increased along with reduced calorie intake, the
possible. They are inappropriate if you are trying for
benefit can be remarkable. Many of the benefits can
be obtained by relatively small degrees of weight
Infertility
This is the most successful treatment but also
the most expensive. You will need to be seen
1) If overweight, weight reduction is important.
by an infertility specialist for this treatment.
(See IVF patient information sheet for further
2) Clomifene is a simple drug treatment. It is given
for 5 days starting on day 2 of your menstrual
J. Med. Chem. 2004, 47, 5555-5566 Increased Anti-P-glycoprotein Activity of Baicalein by Alkylation on the A Ring Yashang Lee,†,| Hosup Yeo,†,‡,| Shwu-Huey Liu,§ Zaoli Jiang,§ Ruben M. Savizky,‡ David J. Austin,‡ andYung-chi Cheng*,† Department of Pharmacology, Yale University School of Medicine, Department of Chemistry, Yale University, andPhytoCeutica, Inc., New Haven, C
March 12, 2013 Candidates to the BoD and Audit Commission approved Ekaterinburg (Ural Federal District, Russia) –IDGC of Urals, OAO (MICEX: MRKU) reports on the results of BoD session. March 06, 2013 saw an extramural BoD meeting which reviewed a range of managing and corporate issues. Review of shareholder proposals to introduce issues into the AGM’s agenda and no