Fujifilm Sericol Plastisol Flow Thinner ZE591 AUSTelephone: +61 2 9466 2600Emergency Tel: +61 1800 039 008Emergency Tel: +61 3 9573 3112Fax: +61 2 9938 1975 HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to NOHSC Crite ria, and ADG Code .
■ Irritating to eyes respiratory system and skin.
■ Keep container in a well ventilated place.
■ May cause SENSITISATION by skin contact.
■ Avoid exposure - obtain special instructions before use.
■ To clean the floor and all objects contaminated by this material use water and ■ HARMFUL - May cause lung damage if swallowed.
■ Inhalation may produce health damage*.
■ Cumulative effects may result following exposure*.
■ Keep away from food drink and animal feeding stuffs.
■ In case of contact with eyes rinse with plenty of water and contact Doctor or ■ May possibly be harmful to the foetus/ embryo*.
■ Repeated exposure potentially causes skin dryness ■ If swallowed IMMEDIATELY contact Doctor or Poisons Information Centre (show ■ Vapours potentially cause drowsiness and dizziness*.
Immediately give a glass of water.
First aid is not generally required. If in doubt, contact a Poisons Information Centre or a doctor.
If spontaneous vomiting appears imminent or occurs, hold patient's head down, lower than their hips to help avoid possible aspiration ofvomitus.
EYE■ If this product comes in contact with the eyes: Wash out immediately with fresh running water.
Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper andlower lids.
Seek medical attention without delay; if pain persists or recurs seek medical attention.
Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.
Immediately remove all contaminated clothing, including footwear.
Flush skin and hair with running water (and soap if available).
Seek medical attention in event of irritation.
If fumes or combustion products are inhaled remove from contaminated area.
Lay patient down. Keep warm and rested.
Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid procedures.
Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as trained.
Perform CPR if necessary.
NOTES TO PHYSICIAN■ Any material aspirated during vomiting may produce lung injury. Therefore emesis should not be induced mechanically or pharmacologically.
Mechanical means should be used if it is considered necessary to evacuate the stomach contents; these include gastric lavage after endotrachealintubation. If spontaneous vomiting has occurred after ingestion, the patient should be monitored for difficult breathing, as adverse effects ofaspiration into the lungs may be delayed up to 48 hours.
Treat symptomatically.
for simple esters:--------------------------------------------------------------BASIC TREATMENT-------------------------------------------------------------- Establish a patent airway with suction where necessary.
Watch for signs of respiratory insufficiency and assist ventilation as necessary.
Administer oxygen by non-rebreather mask at 10 to 15 l/min.
Monitor and treat, where necessary, for pulmonary oedema .
Monitor and treat, where necessary, for shock.
DO NOT use emetics. Where ingestion is suspected rinse mouth and give up to 200 ml water (5 ml/kg recommended) for dilution wherepatient is able to swallow, has a strong gag reflex and does not drool.
--------------------------------------------------------------ADVANCED TREATMENT-------------------------------------------------------------- Consider orotracheal or nasotracheal intubation for airway control in unconscious patient or where respiratory arrest has occurred.
Positive-pressure ventilation using a bag-valve mask might be of use.
Monitor and treat, where necessary, for arrhythmias.
Start an IV D5W TKO. If signs of hypovolaemia are present use lactated Ringers solution. Fluid overload might create complications.
Drug therapy should be considered for pulmonary oedema.
Hypotension with signs of hypovolaemia requires the cautious administration of fluids. Fluid overload might create complications.
Treat seizures with diazepam.
Proparacaine hydrochloride should be used to assist eye irrigation.
--------------------------------------------------------------EMERGENCY DEPARTMENT-------------------------------------------------------------- Laboratory analysis of complete blood count, serum electrolytes, BUN, creatinine, glucose, urinalysis, baseline for serum aminotransferases(ALT and AST), calcium, phosphorus and magnesium, may assist in establishing a treatment regime. Other useful analyses include anion andosmolar gaps, arterial blood gases (ABGs), chest radiographs and electrocardiograph.
Positive end-expiratory pressure (PEEP)-assisted ventilation may be required for acute parenchymal injury or adult respiratory distresssyndrome.
Consult a toxicologist as necessary.
Alcohol stable foam.
Dry chemical powder.
BCF (where regulations permit).
Carbon dioxide.
Water spray or fog - Large fires only.
Alert Fire Brigade and tell them location and nature of hazard.
Wear breathing apparatus plus protective gloves for fire only.
Prevent, by any means available, spillage from entering drains or water courses.
Use fire fighting procedures suitable for surrounding area.
DO NOT approach containers suspected to be hot.
Cool fire exposed containers with water spray from a protected location.
If safe to do so, remove containers from path of fire.
Equipment should be thoroughly decontaminated after use.
Slight fire hazard when exposed to heat or flame.
Heating may cause expansion or decomposition leading to violent rupture of containers.
On combustion, may emit toxic fumes of carbon monoxide (CO).
May emit acrid smoke.
Mists containing combustible materials may be explosive.
Combustion products include: carbon dioxide (CO2), other pyrolysis products typical of burning organic material.
May emit poisonous fumes.
May emit corrosive fumes.
FIRE INCOMPATIBILITY■ Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine bleaches, pool chlorine etc. as ignition may result Limit exposure duration to 1 BA set 30 mins.
Clean up all spills immediately.
Avoid breathing vapours and contact with skin and eyes.
Control personal contact by using protective equipment.
Contain and absorb spill with sand, earth, inert material or vermiculite.
Wipe up.
Place in a suitable, labelled container for waste disposal.
Clear area of personnel and move upwind.
Alert Fire Brigade and tell them location and nature of hazard.
Wear breathing apparatus plus protective gloves.
Prevent, by any means available, spillage from entering drains or water course.
Stop leak if safe to do so.
Contain spill with sand, earth or vermiculite.
Collect recoverable product into labelled containers for recycling.
Neutralise/decontaminate residue.
Collect solid residues and seal in labelled drums for disposal.
Wash area and prevent runoff into drains.
After clean up operations, decontaminate and launder all protective clothing and equipment before storing and re-using.
If contamination of drains or waterways occurs, advise emergency services.
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
DO NOT allow clothing wet with material to stay in contact with skinAvoid all personal contact, including inhalation.
Wear protective clothing when risk of exposure occurs.
Use in a well-ventilated area.
Avoid contact with moisture.
Avoid contact with incompatible materials.
When handling, DO NOT eat, drink or smoke.
Keep containers securely sealed when not in use.
Avoid physical damage to containers.
Always wash hands with soap and water after handling.
Work clothes should be laundered separately. Launder contaminated clothing before re-use.
Use good occupational work practice.
Observe manufacturer's storing and handling recommendations.
Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions are maintained.
Polyethylene or polypropylene container.
Packing as recommended by manufacturer.
Check all containers are clearly labelled and free from leaks.
Esters react with acids to liberate heat along with alcohols and acids.
Strong oxidising acids may cause a vigorous reaction with esters that is sufficiently exothermic to ignite the reaction products.
Heat is also generated by the interaction of esters with caustic solutions.
Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Esters may be incompatible with aliphatic amines and nitrates.
Store in original containers.
Keep containers securely sealed.
Store in a cool, dry, well-ventilated area.
Store away from incompatible materials and foodstuff containers.
Protect containers against physical damage and check regularly for leaks.
Observe manufacturer's storing and handling recommendations.
The following materials had no OELs on our records • bis(2-ethylhexyl) maleate: CAS:142-16-5 Safety glasses with side shields.
Chemical goggles.
Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document, describingthe wearing of lens or restrictions on use, should be created for each workplace or task. This should include a review of lens absorption andadsorption for the class of chemicals in use and an account of injury experience. Medical and first-aid personnel should be trained in theirremoval and suitable equipment should be readily available. In the event of chemical exposure, begin eye irrigation immediately and removecontact lens as soon as practicable. Lens should be removed at the first signs of eye redness or irritation - lens should be removed in a cleanenvironment only after workers have washed hands thoroughly. [CDC NIOSH Current Intelligence Bulletin 59] Wear chemical protective gloves, eg. PVC.
Wear safety footwear or safety gumboots, eg. Rubber The material may produce skin sensitisation in predisposed individuals. Care must be taken, when removing gloves and other protectiveequipment, to avoid all possible skin contact.
Contaminated leather items, such as shoes, belts and watch-bands should be removed and destroyed.
Do NOT use natural rubber, butyl rubber, EPDM or polystyrene-containing materials.
Suitability and durability of glove type is dependent on usage. Important factors in the selection of gloves include: such as: frequency and duration of contact,chemical resistance of glove material,glove thickness anddexterity Select gloves tested to a relevant standard (e.g. Europe EN 374, US F739).
When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time greater than 240minutes according to EN 374) is recommended.
When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN374) is recommended.
Contaminated gloves should be replaced.
Gloves must only be worn on clean hands. After using gloves, hands should be washed and dried thoroughly. Application of a non-perfumedmoisturiser is recommended.
OTHER■ Overalls.
P.V.C. apron.
Barrier cream.
Skin cleansing cream.
Eye wash unit.
ENGINEERING CONTROLS■ Local exhaust ventilation usually required. If risk of overexposure exists, wear approved respirator. Correct fit is essential to obtain adequate protection. Supplied-air type respirator may be required in special circumstances. Correct fit is essential to ensure adequate protection.
An approved self contained breathing apparatus (SCBA) may be required in some situations.
Provide adequate ventilation in warehouse or closed storage area.
Coloured liquid with a characteristic odour; does not mix with water.
Does not mix with water.
Floats on water.
Hazardous polymerisation will not occur.
For incompatible materials - refer to Section 7 - Handling and Storage.
■ HARMFUL - May cause lung damage if swallowed.
■ May cause SENSITISATION by skin contact.
■ Irritating to eyes, respiratory system and skin.
■ May possibly be harmful to the foetus/embryo*.
■ Vapours may cause dizziness or suffocation.
■ Cumulative effects may result following exposure*.
■ Inhalation may produce health damage*.
■ Repeated exposure potentially causes skin dryness and cracking*.
■ Vapours potentially cause drowsiness and dizziness*.
TOXICITY AND IRRITATION■ For Group B aliphatic esters of mono-alcohols and diacids (diesters)According to a classification scheme described by the American Chemistry Council' Aliphatic Esters Panel, Group B substances are comprisedof aliphatic esters derived from linear diacids and monofunctional alcohols. The diacids include maleic (C4), adipic (C6), azelaic (C9) and sebacic(C10) acid. The monofunctional alcohols most common in the diesters are in the C8 to C13 carbon range, although methyl, isopropyl and butyloccur in some diesters.
Due to the physicochemical properties of the diesters (e.g., viscosity, pour point), they have widespread applications as lubricants, solvents, andplasticisers. The linear diacid portion of the diester contributes to the good viscosity index while branching in the alcohol portion provides goodpour point characteristics. Because diesters have good polarity characteristics, they are useful as solvents.
Acute toxicity: Most of the diesters in Group B are higher alkyl (>C8) adipates, azelates and sebacates and these diesters generally have a loworder of toxicity. Oral rat LD50 values ranged from >2 g/kg to >64 g/kg.
Metabolism of the diesters in animals is expected to lead to the generation of corresponding diacids: namely, maleic, adipic, azelaic and sebacicacid and the corresponding linear or branched alcohol (e.g., 2-ethylhexyl, I-methylheptyl, isooctyl, isononyl, isodecyl, tridecyl alcohols). Thesediacids and alcohols can further be metabolized and conjugated to products that are excreted in the urine The diacids and alcohols have a loworder of toxicityRepeated Dose Toxicity. Data on repeated dose toxicity have been reported for diisononyl adipate and tridecyl adipate. In 90-day toxicity studies,rats were administered diisononyl adipate (CAS 33703-08-l) in the diet at levels equivalent to 0,50, 150 and 500 mg/kg/day. The NOAEL was 500mg/kg/day. Feeding studies were also carried out in beagle dogs for 13 weeks at dietary concentrations of 0,0.3, 1 and 3% (increased to 6% atweek 9). The NOAEL was determined to be 1% in the diet or approximately 274 mg/kg/day. In another 13-week study, ditridecyl adipate was welltolerated in rats given dermal doses of 800 and 2000 mg/kg/day.
For adipic acid di-C7-9 branched and linear alkyl ester (CAS 685 15-75-3), rats were fed 0,O. 1,0.5 and 2.5% of the test substance in the diet. Nosignificant signs of toxicity were observed in male and female rats administered the test material in the diet at concentrations up to 2.5% for aperiod of 13 weeks. The NOAEL was 2.5% for both sexes (males -1300 mg/kg; females -1800 mg/kg). In the 90-day dietary studies with2-ethylhexyl adipate (CAS 103-23-l), the NOAEL was -300 mg/kg/day in rats and -230 mg/kg/day in mice. The LOAEL was -600 mg/kg/day in rats and -460 mg/kg/day in mice. Hepatic hypertrophy and increased peroxisomal enzyme activity occurred in rats and mice; however, there were no adverse effects on the liver.
Reproductive toxicity: Di-2-ethylhexyl adipate (DEHA)(CAS 103-23-l) has been evaluated for reproductive effects in a one-generation study. Testdiets, up to 1080 mg/kg/day, were fed continuously throughout the study (18-19 weeks of exposure). No effects were seen on male or femalefertility. However, at the highest dose, there was a reduction in body weight in the dams, and reduction in offspring body weight, total litter weightand litter size. The NOAEL and LOAEL for this study was 170 and 1080 mg/kg/day, respectively. In 13-week dermal studies with ditridecyl adipate,there was no sperm morphological changes observed in male rats treated at levels of 2000 mg/kg. Increases in organ weight of the epididymidesand uterus were observed at dermal exposure to 2000 mg/kg but not at 800 mg/kg. In a 19-week oral feeding study with sebacic acid, bis(2-ethylhexyl) ester (CAS 122~62-3), no adverse reproductive effects were reported for this material. Dibutyl maleate has been evaluated in anOECD reproductive/developmental toxicity screening test (oral gavage) and no adverse effects on reproduction were reported.
Since these four materials cover the carbon number range of C12-C32 for the diesters and because of the chemical similarity of the alkyl diesters,the available reproductive toxicity data should be sufficient for read-across assessment of most of the other diesters in Group B.
Developmental toxicity: No evidence of developmental toxicity was observed at dose levels of 1000 and 4000 mg/kg/day after oral gavage of adipicacid, di-C7-9 branched and linear alkyl ester (CAS 685 15-75-3). Slight maternal toxicity (reduced body weight) and embryotoxicity (reduced foetalweight) was observed at the highest dose (7000 mg/kg/day). The NOAEL for maternal and developmental toxicity was 4000 mg/kg/day. Noadverse developmental effects were reported for dibutyl maleate in an OECD reproductive/developmental screening studyThe developmental toxicity has also been evaluated for adipic acid, bis(2-ethylhexyl) ester (CAS 103-23-l) by dietary exposure. Pregnant ratsadministered 2-ethylhexyl adipate in the diet throughout gestation showed reduced body weight at dietary equivalent doses of 1080 mg/kg/day. At1080 mg/kg/day, implantation fetal loss was evident; however, no gross, skeletal or visceral abnormalities were observed. LOAEL was 1080mg/kg/day and NOAEL was 170 mg/kg/day (developmental toxicity). The developmental toxicity data from these three studies provide sufficientdata for the read-across assessment of most of the other diesters in Group B due to their chemical structural similarities.
Genotoxicity: Adipic acid diisononyl ester and sebacic acid bis(2-ethylhexyl) ester] were shown to be negative in the Ames assay. In addition,diisononyl adipate was negative in the mouse lymphoma assay. Adipic acid, bis(2-ethylhexyl) ester has also been evaluated for mutagenicity andwas found to be negative in both the Ames and mouse lymphoma assays. It has also been reported that dibutyl maleate (CAS 105- 76-0) isnegative in the Ames assay Adipic acid, ditridecyl ester (CAS 16958-92-2) was negative in the micronucleus assay. Adipic acid bis(2- ethylhexyl) ester (CAS 103-23-l), alsodid not cause chromosomal aberrations in the Chinese hamster ovary cell assay or the mouse micronucleus test . Since these two adipatescover the carbon number range of C22-C32 for the diesters, it is unlikely that the substances in Group B are chromosomal mutagens. In addition,dibutyl maleate (C12) has been shown to be negative in the mouse micronucleus test in vivo.
The material may be irritating to the eye, with prolonged contact causing inflammation. Repeated or prolonged exposure to irritants may produceconjunctivitis.
The material may cause skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production ofvesicles, scaling and thickening of the skin.
Containers may still present a chemical hazard/ danger when empty.
Return to supplier for reuse/ recycling if possible.
If container can not be cleaned sufficiently well to ensure that residuals do not remain or if the container cannot be used to store the sameproduct, then puncture containers, to prevent re-use, and bury at an authorised landfill.
Where possible retain label warnings and MSDS and observe all notices pertaining to the product.
Legislation addressing waste disposal requirements may differ by country, state and/ or territory. Each user must refer to laws operating in theirarea. In some areas, certain wastes must be tracked.
A Hierarchy of Controls seems to be common - the user should investigate: ReductionReuseRecyclingDisposal (if all else fails) This material may be recycled if unused, or if it has not been contaminated so as to make it unsuitable for its intended use. If it has beencontaminated, it may be possible to reclaim the product by filtration, distillation or some other means. Shelf life considerations should also beapplied in making decisions of this type. Note that properties of a material may change in use, and recycling or reuse may not always beappropriate.
DO NOT allow wash water from cleaning or process equipment to enter drains.
It may be necessary to collect all wash water for treatment before disposal.
In all cases disposal to sewer may be subject to local laws and regulations and these should be considered first.
Where in doubt contact the responsible authority.
Recycle wherever possible.
Consult manufacturer for recycling options or consult local or regional waste management authority for disposal if no suitable treatment ordisposal facility can be identified.
Dispose of by: burial in a land-fill specifically licenced to accept chemical and / or pharmaceutical wastes or incineration in a licencedapparatus (after admixture with suitable combustible material).
Decontaminate empty containers. Observe all label safeguards until containers are cleaned and destroyed.
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS: UN, IATA, IMDG REGULATIONSRegulations for ingredientsbis(2-ethylhexyl) maleate (CAS: 142-16-5) is found on the following regulatory lists; "Australia Inventory of Chemical Substances (AICS)","International Council of Chemical Associations (ICCA) - High Production VolumeList","OECD Representative List of High Production Volume (HPV) Chemicals"No data for Fujifilm Sericol Plastisol Flow Thinner ZE591 (CW: 4673-35) Denmark Advisory list for selfclassification of dangerous substances Substance CAS Suggested codes bis(2- ethylhexyl) maleate 142- 16- 5 ■ Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review bythe Chemwatch Classification committee using available literature references.
A list of reference resources used to assist the committee may be found
■ The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or available engineering controls must be considered.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission from CHEMWATCH. TEL (+61 3) 9572 4700.


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